3D Realms and their Bombshell of a game
Bombshell, a "an isometric action role-playing game" from developer 3D Realms, puts you in control of Shelly 'Bombshell' Harrison must strong-arm her way across 4 planets in an Unreal Engine-powered galactic adventure to rescue the president from an apocalyptic alien threat."
It's trope-y as all hell in that Duke Nukem kind of way thanks to Shelly's modifiable robotic arm, motorcycle, over the top gun, and the alien race that looks EXACTLY like predators, but all of this is coming from a developer who has working on a new Duke Nukem game for years now, so that's not necessarily a bad thing.
If you like playing as the cool badass character that feels no fear running and shooting down corridors while defending the human race on your motorcycle from aliens, then Bombshell is sounding like a good canidate to add to your game collection.
Bombshell will be releasing "for PC and consoles" later this year and will be playable at Quakecon.