Guild Wars 2 Action Combat Mod Approved
A few days ago a workaround for Guild Wars 2 was released that gives players the ability to use crosshair targeting, eliminates the need to use Tab targeting and cursor targeting, and allows you to turn the camera without constantly needing to hold down the mouse buttons. In addition, the workaround also allows you to bind actions to the scroll wheel.
The "mod" uses the program AutoHotkey and Guild Wars 2's in game auto targeting options. It provides a more immediate action game like targeting system, not unlike the one used in recent MMO Tera.
The mod and developer response can be found here.